Evocalcet Impurity 4 HCl CAS 1666124-30-6 (free base)
| CAS No. | 1666124-30-6 (free base) |
| Molecular Formula | C26H30N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Evocalcet Impurity 4 HCl (CAS 1666124-30-6 (free base), C26H30N2O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Evocalcet Impurity 4 HCl (C26H30N2O2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Evocalcet Impurity 4 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H30N2O2 HCl |
| Molecular Weight | 439.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Evocalcet Standards
- Evocalcet Impurity 27 (CAS 1039631-63-4)
- Evocalcet Impurity 30 (CAS 1039631-66-7)
- Evocalcet Impurity 29 (CAS 1092366-92-1)
- Evocalcet Impurity 73 (CAS 15297-34-4)
- Evocalcet Impurity 33 HCl (CAS 1666124-29-3)
- Evocalcet impurity 52 (CAS 1666124-30-6)
- Evocalcet Impurity 17 (CAS 210367-24-1)
- Evocalcet impurity 53 (CAS 2107154-97-0)
Recommended Standards
- Pyronaridine Impurity 6 (CAS CATO-C4X-29786)
- Amiodarone EP Impurity D (CAS 1951-26-4)
- Amlodipine Impurity 76 (CAS CATO-C4X-109576)
- 2-Methyl-2-(4-(4-nitrophenyl)piperazin-1-yl)propanamide (CAS 256958-68-6)
- 2-Methoxy-6-(quinolin-8-yloxymethyl)-benzoic acid (CAS 1171924-48-3)
- 2-[methyl(propan-2-yl)amino]benzaldehyde (CAS 1021239-93-9)
- 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane (CAS 333-36-8)
- N1,N1-dimethyl-1-(o-tolyl)ethane-1,2-diamine (CAS 928000-19-5)
- (4-Bromo-2-(trifluoromethyl)phenyl)hydrazine hydrochloride (CAS 221092-41-7)
- Semaglutide impurity 103 (CAS 1446013-07-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com